RIDUTOX Injection Glutathione is now considered as the best selling Glutathione brand in Italy.
Ridutox Glutathione Skin Whitening Injection
Ridutox Glutathione – Glutathione is a linear tripeptide with a sulfhydryl group containing L-glutamine, L-cysteine and glycine. It plays an important role in protecting the cells of the body, being a powerful antioxidant. In the human body, a lack of glutathione leads to the emergence of many diseases, such as Parkinson’s disease, type I tyrosinemia, alcohol poisoning and others. In vivo and in vitro experiments have shown that a lack of glutathione can lead to mitochondrial damage and cell death caused by an increase in the number of toxic oxygen species, leading to an increase in the number of free radicals.
Glutathione is able to prevent cell damage by combining with toxic substances and / or their metabolites. Neutralization of xenobiotics with glutathione can be carried out in three different ways: by conjugation of the substrate with glutathione, as a result of nucleophilic substitution, and as a result of the reduction of organic peroxides to alcohols.
Dosage form of Ridutox Glutathione
Lyophilized powder for the preparation of a solution for intravenous and intramuscular administration.
Method of administration and dosage
For intravenous administration, the contents of the vial are dissolved in 250-500 ml of 0.9% sodium chloride solution. The drug solution is used immediately after preparation; reuse of the remaining solution is not allowed.
In severe forms of hepatitis of various etiology – 1.2–2.4 g intravenously per day for 30 days in the form of infusions. With alcoholic hepatitis – 1.8 g intravenously per day for 14-30 days in the form of infusion.
With alcoholic cirrhosis – 1.2 g intravenously per day for 30 days in the form of infusion.
With hepatic steatosis – 1.8 g intravenously per day for 30 days as an infusion.
Intravenous infusion must be performed slowly.
For intramuscular administration: 0.3 g is diluted in 3 ml of 0.9% sodium chloride solution, 0.6 g is diluted in 4 ml of 0.9% sodium chloride solution. The drug must be completely dissolved in the solvent. The solution should be clear and colorless. 1.2 g and 1.8 g are not administered intramuscularly.
Given the high likelihood of existing violations of the liver or heart, the dose of Glation should be selected with caution in elderly patients, starting with the lower limit of the dose range.
In severe forms of hepatitis of various etiologies, it is not recommended to exceed 0.6-1.2 g intravenously per day for 30 days in the form of infusions.
In alcoholic hepatitis, it is not recommended to exceed 0.9 g intravenously per day for 14-30 days in the form of infusion.
In alcoholic cirrhosis, it is not recommended to exceed 0.6 g intravenously per day for 30 days as an infusion.
In hepatic steatosis, it is not recommended to exceed 0.9 g intravenously per day for 30 days as an infusion.
Allergic reactions, a decrease in blood pressure, a decrease or increase in heart rate, heart palpitations, dyspeptic disorders, which disappear after stopping the use of the drug, are possible.
Overdose cases were not recorded. If an overdose occurs, symptomatic therapy should be used.
Avoid combined use with menadione sodium bisulfite, cyanocobalamin, calcium pantothenate, sulfa drugs and tetracyclines.
If symptoms of allergy appear, you must stop using the drug.
Influence on the ability to drive vehicles and mechanisms
In view of the possible manifestations of side effects of the drug, the drug should be used with caution in persons driving vehicles and servicing mechanisms.
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